Sean Gaine Selected Research

Pulmonary Hypertension

1/2023	Exploration of physical activity knowledge, preferences and support needs among pulmonary hypertension patients.
10/2021	Pulmonary hypertension and home-based (PHAHB) exercise intervention: protocol for a feasibility study.
1/2021	Perioperative management of patients with pulmonary hypertension undergoing non-cardiothoracic, non-obstetric surgery: a systematic review and expert consensus statement.
5/2016	Dynamic Risk Stratification of Patient Long-Term Outcome After Pulmonary Endarterectomy: Results From the United Kingdom National Cohort.
3/2016	Long-Term Outcome of Patients With Chronic Thromboembolic Pulmonary Hypertension: Results From an International Prospective Registry.
1/2015	Elevated plasma CXCL12α is associated with a poorer prognosis in pulmonary arterial hypertension.
11/2011	Chronic thromboembolic pulmonary hypertension (CTEPH): results from an international prospective registry.
10/2009	Guidelines for the diagnosis and treatment of pulmonary hypertension: the Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS), endorsed by the International Society of Heart and Lung Transplantation (ISHLT).
9/2006	Temporal trends and drug exposures in pulmonary hypertension: an American experience.

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Sean Gaine Research Topics

Disease

23	Pulmonary Arterial Hypertension 03/2023 - 11/2011
9	Pulmonary Hypertension 01/2023 - 09/2006
5	Disease Progression 01/2023 - 01/2019
4	Venous Thromboembolism 12/2020 - 11/2011
3	COVID-19 01/2022 - 01/2021
2	Connective Tissue Diseases (Connective Tissue Disease) 01/2020 - 01/2017
2	Lung Diseases (Lung Disease) 01/2020 - 06/2012
1	Systemic Scleroderma (Systemic Sclerosis) 03/2024
1	Fibrosis (Cirrhosis) 01/2024
1	Lung Neoplasms (Lung Cancer) 01/2024
1	Asthma (Bronchial Asthma) 11/2023
1	Mediastinal Emphysema (Pneumomediastinum) 11/2023
1	Thrombophilia 01/2022
1	Fatigue 10/2021
1	Venous Thrombosis (Deep-Vein Thrombosis) 12/2020
1	Pulmonary Embolism 12/2020
1	Congenital Heart Defects (Congenital Heart Defect) 01/2019
1	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2018
1	Mixed Connective Tissue Disease (MCTD) 01/2018
1	Castleman Disease (Castleman's Disease) 01/2018
1	Rheumatoid Arthritis 01/2018
1	Hypertension (High Blood Pressure) 07/2017
1	Chronic Obstructive Pulmonary Disease (COPD) 03/2016
1	Heart Failure 03/2016
1	Coronary Disease (Coronary Heart Disease) 03/2016
1	Pain (Aches) 12/2015
1	Nausea 12/2015
1	Headache (Headaches) 12/2015
1	Diarrhea 12/2015
1	Hypoxia (Hypoxemia) 08/2008
1	Familial Primary Pulmonary Hypertension 09/2006

Drug/Important Bio-Agent (IBA)

13	selexipagIBA 01/2023 - 12/2015
7	Epoprostenol (Prostacyclin)FDA LinkGeneric 01/2021 - 12/2015
6	Epoprostenol ReceptorsIBA 01/2022 - 12/2015
3	edoxabanIBA 12/2020 - 01/2018
2	Interleukin-6 (Interleukin 6)IBA 01/2022 - 01/2018
2	Phosphodiesterase 5 InhibitorsIBA 01/2020 - 12/2015
2	Endothelin Receptor AntagonistsIBA 01/2020 - 12/2015
1	Immunoglobulins (Immunoglobulin)IBA 01/2024
1	Immunoglobulin G (IgG)IBA 01/2024
1	A 19IBA 11/2023
1	Oxygen (Dioxygen)IBA 11/2023
1	Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA 01/2022
1	Heparin (Liquaemin)FDA LinkGeneric 01/2022
1	Thrombin FDA Link 01/2022
1	Platelet Factor 4IBA 01/2021
1	Adenosine Diphosphate (ADP)IBA 01/2021
1	Thrombopoietin (c-mpl Ligand)IBA 01/2021
1	P-SelectinIBA 01/2021
1	SelectinsIBA 01/2021
1	Warfarin (Coumadin)FDA LinkGeneric 12/2020
1	treprostinil FDA Link 01/2020
1	Carbon MonoxideIBA 01/2020
1	Brain Natriuretic Peptide (Natrecor)FDA Link 01/2019
1	pro-brain natriuretic peptide (1-76)IBA 01/2019
1	tocilizumab (atlizumab)FDA Link 01/2018
1	Interleukin-6 Receptors (Interleukin 6 Receptor)IBA 01/2018
1	macitentanIBA 01/2018
1	Interferon-betaIBA 05/2015
1	CytokinesIBA 01/2015
1	LigandsIBA 06/2012
1	Chemokine CXCL12IBA 08/2008
1	Proteins (Proteins, Gene)FDA Link 08/2008
1	Dexfenfluramine (Redux)IBA 09/2006
1	FenfluramineIBA 09/2006

Therapy/Procedure

15	Therapeutics 03/2024 - 11/2011
2	Critical Care (Surgical Intensive Care) 01/2021 - 01/2021
2	Endarterectomy (Thromboendarterectomy) 05/2016 - 11/2011
1	Activities of Daily Living (ADL) 10/2021
1	Obstetric Surgical Procedures 01/2021
1	Operative Surgical Procedures 01/2021
1	Immunomodulation 01/2018
1	Perioperative Period 05/2016
1	Lung Transplantation 10/2009